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PI3 Kinase p110 delta Recombinant Rabbit mAb (S-M0023)

Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform,PI3-kinase subunit delta,PI3K-delta,PI3Kdelta,PtdIns-3-kinase subunit delta,5-bisphosphate 3-kinase 110 kDa catalytic subunit delta (PtdIns-3-kinase subunit p110-delta,p110delta)

价格 ￥600.00 （ 供应商现货 ： 3-5个工作日）
货号 S0B60082
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产品介绍

产品介绍 评论(0)

产品规格

  • 宿主来源

    Rabbit

  • 抗原名称

    PIK3CD

  • 分子别名

    Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform; PI3-kinase subunit delta; PI3K-delta; PI3Kdelta; PtdIns-3-kinase subunit delta; Phosphatidylinositol 4,5-bisphosphate 3-kinase 110 kDa catalytic subunit delta (PtdIns-3-kinase subunit p110-delta; p110delta)

  • 细胞定位

    Cytoplasm

  • Accession

    O00329

  • 克隆号

    S-M0023

  • 抗体类型

    Recombinant mAb

  • 抗体同种型

    IgG

  • 反应种属 ?

    Hu, Ms, Rt

  • 阳性样本

    Raji, Jurkat, RAW264.7, mouse thymus, rat spleen

  • 纯化方式

    Protein A

  • 浓度

    2 mg/ml

  • 标记

    Unconjugated

  • 性状

    Liquid

  • 缓冲体系

    PBS, 40% Glycerol, 0.05% BSA, 0.02% sodium azide

  • 储存条件

    12 months from date of receipt / reconstitution, -20 °C as supplied

  • 应用

    WB

  • 稀释度

    应用 稀释度 推荐种属
    WB 1:500-1:1000 Hu, Ms, Rt
背景介绍

  • PIK3CD is a gene that encodes a protein which is an integral part of the phosphatidylinositol 3-kinase (PI3K) signaling pathway. This pathway is crucial for various cellular functions including cell growth, proliferation, survival, and metabolism. The PIK3CD protein specifically refers to the delta isoform of the catalytic subunit of PI3K. It is predominantly expressed in immune cells and plays a significant role in the regulation of immune responses. Abnormal activation or mutations in the PIK3CD gene can lead to a range of diseases including certain types of leukemia and other immune-related disorders. Understanding its function and regulation is important for developing targeted therapies in cancer and immune system disorders.

  • 免疫印迹

    • WB result of PI3 Kinase p110 delta Recombinant Rabbit mAb
      Primary antibody: PI3 Kinase p110 delta Recombinant Rabbit mAb at 1/1000 dilution
      Lane 1: Raji whole cell lysate 20 µg
      Lane 2: Jurkat whole cell lysate 20 µg
      Secondary antibody: Goat Anti- rabbit IgG, (H+L), HRP conjugated at 1/10000 dilution
      Predicted MW: 119 kDa
      Observed MW: 115 kDa
      This blot was developed with high sensitivity substrate

    • WB result of PI3 Kinase p110 delta Recombinant Rabbit mAb
      Primary antibody: PI3 Kinase p110 delta Recombinant Rabbit mAb at 1/1000 dilution
      Lane 1: RAW264.7 whole cell lysate 20 µg
      Lane 2: mouse thymus lysate 20 µg
      Secondary antibody: Goat Anti- rabbit IgG, (H+L), HRP conjugated at 1/10000 dilution
      Predicted MW: 119 kDa
      Observed MW: 115 kDa
      This blot was developed with high sensitivity substrate

    • WB result of PI3 Kinase p110 delta Recombinant Rabbit mAb
      Primary antibody: PI3 Kinase p110 delta Recombinant Rabbit mAb at 1/1000 dilution
      Lane 1: rat spleen lysate 20 µg
      Secondary antibody: Goat Anti- rabbit IgG, (H+L), HRP conjugated at 1/10000 dilution
      Predicted MW: 119 kDa
      Observed MW: 115 kDa
      This blot was developed with high sensitivity substrate

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