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Rat抗原名称
CD8β分子别名
T-cell surface glycoprotein CD8 beta chain; Lymphocyte antigen 3; T-cell membrane glycoprotein Ly-3; T-cell surface glycoprotein Lyt-3; Cd8b1; Ly-3; Lyt-3; Lyt3; Cd8bAccession
P10300克隆号
53-5.8抗体类型
Rat mAb抗体同种型
IgG1,k反应种属 ?
Ms阳性样本
BALB/c mouse splenocytes纯化方式
Protein G浓度
2 mg/ml标记
Unconjugated性状
Liquid缓冲体系
PBS pH7.4
储存条件
12 months from date of receipt / reconstitution, 2 to 8 °C as supplied
应用
FCM
稀释度
应用 稀释度 推荐种属 FCM 1:100 Ms
CD8β is a protein that, along with CD8α, forms the CD8 co - receptor complex on the surface of cytotoxic T cells. This complex plays a crucial role in the immune response by facilitating the interaction between cytotoxic T cells and antigen - presenting cells. CD8β helps stabilize the binding of the T cell receptor to MHC class I molecules on the antigen - presenting cell, thereby enhancing the specificity and efficiency of the T cell - mediated immune response. This interaction is essential for the activation of cytotoxic T cells, which can then target and destroy infected or malignant cells.
流式分析
Flow cytometric analysis of BALB/c mouse splenocytes labelling CD8β (Lyt 3.2) antibody at 1/200 (1 μg) dilution/ (Right panel) compared with a Rat IgG1, κ Isotype Control / (left panel). Goat Anti-Rat IgG Alexa Fluor® 488 was used as the secondary antibody. Then cells were stained with CD8a - APC antibody separately.







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