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宿主来源
Rabbit抗原名称
NCR1分子别名
Natural cytotoxicity triggering receptor 1; Activating receptor 1 (mAR-1); Lymphocyte antigen 94; Natural killer cell p46-related protein (NK-p46; NKp46; mNKp46); CD335; Ly94; Ncr1免疫原
Recombinant Protein细胞定位
Cell membraneAccession
Q8C567克隆号
S-2176-37抗体类型
Recombinant mAb抗体同种型
IgG反应种属 ?
Ms纯化方式
Protein A浓度
2 mg/ml标记
Unconjugated性状
Liquid缓冲体系
PBS pH7.4
储存条件
12 months from date of receipt / reconstitution, 2 to 8 °C as supplied
应用
FCM
稀释度
应用 稀释度 推荐种属 FCM Ms
NCR1 (Natural Cytotoxicity Triggering Receptor 1, also known as CD335 or NKp46) is a pivotal activating receptor primarily expressed on the surface of natural killer (NK) cells and belongs to the immunoglobulin superfamily. Acting as a central regulator of NK cell function, it recognizes specific ligands (such as hemagglutinins) expressed on virus-infected cells or tumor cells. This recognition delivers a potent activation signal, triggering the cytotoxic response of NK cells and the release of cytokines (like IFN-γ). It plays an indispensable role as a "first line of defense" in the body's innate immune response against viruses and tumors. Dysregulation of its function is closely associated with the pathogenesis and development of various infectious diseases, cancers, and autoimmune disorders.
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