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Mouse抗原名称
CD193分子别名
C-C chemokine receptor type 3; C C CKR3; C-C CKR-3; CC-CKR-3; CCR-3; CCR3; CKR 3; CKR3; Eosinophil eotaxin receptor; CMKBR3细胞定位
Cell membraneAccession
P51677克隆号
5E8抗体类型
Mouse mAb抗体同种型
IgG2b,k反应种属 ?
Hu阳性样本
Human PBMC纯化方式
Protein A浓度
0.2 mg/ml标记
Alexa Fluor® 488性状
Liquid缓冲体系
PBS, 1% BSA, 0.3% Proclin 300
储存条件
12 months from date of receipt / reconstitution, 2 to 8 °C as supplied
应用
FCM
稀释度
应用 稀释度 推荐种属 FCM 1.25μl per million cells in 100μl volume Hu
CD193, also designated as CCR3, is a seven-transmembrane G protein-coupled receptor that serves as the high-affinity receptor for the CC chemokines eotaxin-1 (CCL11), eotaxin-2 (CCL24), eotaxin-3 (CCL26) and MCP-4 (CCL13) and binds RANTES, MCP-3 and MCP-4 with lower affinity; it is prominently expressed on eosinophils, basophils, mast cells, mononuclear phagocytes, platelets, CD34⁺ hematopoietic progenitors, Th2 lymphocytes and keratinocytes, mediating eosinophil chemotaxis and effector functions in allergic inflammation such as asthma and rhinitis, and also functions as a co-receptor for HIV-1 and HIV-2 entry .
流式分析
Flow cytometric analysis of Human CD193 expression on Human PBMC. Human PBMC (peripheral blood mononuclear cells) were stained with APC Mouse Anti-Human CD16 Antibody and either Alexa Fluor® 488 Mouse IgG2b, κ Isotype Control (Left panel) or Alexa Fluor® 488 Mouse Anti-Human CD193 Antibody (Right panel) at 1.25 μl/test. Flow cytometry and data analysis were performed using BD FACSymphony™ A1 and FlowJo™ software.
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