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产品中心 流式试剂&相关 流式抗体

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Mouse Anti-Human CD199 Antibody (S-3012)

C-C chemokine receptor type 9,C-C CKR-9,CC-CKR-9,CCR-9,G-protein coupled receptor 28,GPR-9-6,CDw199,GPR28,CCR9

价格 ￥600.00 （ 1-2周）
货号 S0B5746
规格
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产品介绍

产品介绍 评论(0)

产品规格

  • 宿主来源

    Mouse

  • 抗原名称

    CD199

  • 分子别名

    C-C chemokine receptor type 9; C-C CKR-9; CC-CKR-9; CCR-9; G-protein coupled receptor 28; GPR-9-6; CDw199; GPR28; CCR9

  • 细胞定位

    Cell membrane

  • Accession

    P51686

  • 克隆号

    S-3012

  • 抗体类型

    Mouse mAb

  • 抗体同种型

    IgG2a,k

  • 反应种属 ?

    Hu

  • 阳性样本

    MOLT-4

  • 纯化方式

    Protein A

  • 浓度

    2 mg/ml

  • 标记

    Unconjugated

  • 性状

    Liquid

  • 缓冲体系

    PBS pH7.4

  • 储存条件

    12 months from date of receipt / reconstitution, 2 to 8 °C as supplied

  • 应用

    FCM

  • 稀释度

    应用 稀释度 推荐种属
    FCM 1:200 Hu
背景介绍

  • CD199 (also designated CCR9) is a ~42 kDa seven-transmembrane G-protein-coupled chemokine receptor that binds the chemokine CCL25 (TECK), is strongly expressed in thymic cortex and small intestinal epithelium, and is highly expressed on CD4+CD8+ double-positive thymocytes and naive CD8+ T cells, as well as on small intestinal B cells, subsets of memory CD4+/CD8+ T cells, and dendritic cells, thereby directing T-cell development in the thymus and lymphocyte homing to gut-associated tissues via the CCR9/CCL25 axis, with dysregulation implicated in inflammatory bowel disease and celiac disease .

  • 流式分析

    • Flow cytometric analysis of Raji (Human Burkitt's lymphoma B lymphocyte, Left) / MOLT-4 (Human lymphoblastic leukemia T lymphoblast, Right) labelling CD199 antibody at 1/200 dilution (1 μg) / (Red) compared with a Mouse IgG2a, κ Isotype control (Black) and an unlabelled control (cells without incubation with primary antibody and secondary antibody) (Blue). Goat Anti - Mouse IgG Alexa Fluor® 488 was used as the secondary antibody.
      Negative control: Raji

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