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产品中心 流式试剂&相关 流式抗体

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Mouse Anti-Human CD193 Antibody (5E8)

C-C chemokine receptor type 3,C C CKR3,C-C CKR-3,CC-CKR-3,CCR-3,CCR3,CKR 3,CKR3,Eosinophil eotaxin receptor,CMKBR3

价格 ￥600.00 （ 供应商现货 ： 3-5个工作日）
货号 S0B5705
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产品介绍

产品介绍 评论(0)

产品规格

  • 宿主来源

    Mouse

  • 抗原名称

    CD193

  • 分子别名

    C-C chemokine receptor type 3; C C CKR3; C-C CKR-3; CC-CKR-3; CCR-3; CCR3; CKR 3; CKR3; Eosinophil eotaxin receptor; CMKBR3

  • 细胞定位

    Cell membrane

  • Accession

    P51677

  • 克隆号

    5E8

  • 抗体类型

    Mouse mAb

  • 抗体同种型

    IgG2b,k

  • 反应种属 ?

    Hu

  • 阳性样本

    Human PBMC

  • 纯化方式

    Protein A

  • 浓度

    2 mg/ml

  • 标记

    Unconjugated

  • 性状

    Liquid

  • 缓冲体系

    PBS pH7.4

  • 储存条件

    12 months from date of receipt / reconstitution, 2 to 8 °C as supplied

  • 应用

    FCM

  • 稀释度

    应用 稀释度 推荐种属
    FCM 1:200 Hu
背景介绍

  • CD193, also designated CCR3, is a seven-transmembrane G protein-coupled receptor that serves as the high-affinity receptor for the CC chemokines eotaxin-1 (CCL11), eotaxin-2 (CCL24), eotaxin-3 (CCL26) and MCP-4 (CCL13) and binds RANTES, MCP-3 and MCP-4 with lower affinity; it is prominently expressed on eosinophils, basophils, mast cells, mononuclear phagocytes, platelets, CD34⁺ hematopoietic progenitors, Th2 lymphocytes and keratinocytes, mediating eosinophil chemotaxis and effector functions in allergic inflammation such as asthma and rhinitis, and also functions as a co-receptor for HIV-1 and HIV-2 entry .

  • 流式分析

    • Flow cytometric analysis of Human PBMC labelling Human CD193 antibody at 1/200 (1 μg) dilution (Right panel) compared with a Mouse IgG2b, κ Isotype Control (Left panel). Goat Anti-Mouse IgG Alexa Fluor® 488 was used as the secondary antibody. Then cells were stained with CD16 - APC Antibody separately.

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