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Mouse抗原名称
CD41a分子别名
Integrin alpha-IIb; GPalpha IIb (GPIIb); Platelet membrane glycoprotein IIb; CD41; GP2B; ITGAB; ITGA2B细胞定位
MembraneAccession
P08514克隆号
HIP8抗体类型
Mouse mAb抗体同种型
IgG1反应种属 ?
Hu阳性样本
human peripheral blood platelets纯化方式
Protein G浓度
0.2 mg/ml标记
Alexa Fluor® 647性状
Liquid缓冲体系
PBS, 1% BSA, 0.3% Proclin 300
储存条件
12 months from date of receipt / reconstitution, 2 to 8 °C as supplied
应用
FCM
稀释度
应用 稀释度 推荐种属 FCM 5μl per million cells in 100μl volume Hu
CD41a, also known as platelet glycoprotein IIb, is a crucial component of the GPIIb/IIIa complex on the platelet membrane. It is a calcium-dependent protein that pairs with CD61 to form the functional fibrinogen receptor, playing a vital role in platelet aggregation and blood clotting. This complex is primarily expressed in normal platelets and megakaryocytes. Additionally, CD41a is one of the first cell surface markers indicative of hematopoietic commitment and is involved in maintaining hematopoietic stem cell activity during embryonic development.
流式分析
Flow cytometric analysis of Human CD41a expression on human peripheral blood platelets. Human peripheral blood platelets were stained with either Alexa Fluor® 647 Mouse IgG1, κ Isotype Control (Black line histogram) or SDT Alexa Fluor® 647 Mouse Anti-Human CD41a Antibody (Red line histogram) at 5 μl/test. Flow cytometry and data analysis were performed using BD FACSymphony™ A1 and FlowJo™ software.
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