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宿主来源
Mouse抗原名称
CD1d分子别名
Antigen-presenting glycoprotein CD1d; Cd1d1; Cd1d细胞定位
Cell membrane, Endoplasmic reticulumAccession
Q63493克隆号
S-R701抗体类型
Mouse mAb抗体同种型
IgG2a,k反应种属 ?
Rt阳性样本
Lewis Rat thymocytes纯化方式
Protein A浓度
0.2 mg/ml标记
Alexa Fluor® 488性状
Liquid缓冲体系
PBS, 1% BSA, 0.3% Proclin 300
储存条件
12 months from date of receipt / reconstitution, 2 to 8 °C as supplied
应用
FCM
稀释度
应用 稀释度 推荐种属 FCM 5μl per million cells in 100μl volume Rt
CD1d is a non-polymorphic, MHC class I-like molecule encoded by the CD1D gene, which is a member of the CD1 family of glycoproteins expressed on the surface of various human antigen-presenting cells. It presents lipid antigens, including phospholipids and glycosphingolipids, to a subset of T cells known as invariant natural killer T (iNKT) cells. When activated by CD1d-presented antigens, iNKT cells rapidly produce Th1 and Th2 cytokines, such as interferon-gamma and interleukin-4. CD1d is also involved in the selection and regulation of iNKT cells. Some known ligands for CD1d include α-galactosylceramide (α-GalCer), a compound derived from a marine sponge, and various microbial and self-antigens.
流式分析
Flow cytometric analysis of Rat CD1d expression on Lewis Rat thymocytes. Lewis Rat thymocytes were stained with Alexa Fluor® 488 Mouse IgG2a, κ Isotype Control (Black line histogram) or SDT Alexa Fluor® 488 Mouse Anti-Rat CD1d Antibody (Red line histogram) at 5 μl/test. Flow cytometry and data analysis were performed using BD FACSymphony™ A1 and FlowJo™ software.
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