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Mouse抗原名称
CD269分子别名
Tumor necrosis factor receptor superfamily member 17; B-cell maturation protein; BCM; BCMA; TNFRSF17细胞定位
Cell membraneAccession
Q02223克隆号
S-R559抗体类型
Mouse mAb抗体同种型
IgG2a,k反应种属 ?
Hu阳性样本
U266B1纯化方式
Protein A浓度
2 mg/ml标记
Unconjugated性状
Liquid缓冲体系
PBS pH7.4
储存条件
12 months from date of receipt / reconstitution, 2 to 8 °C as supplied
应用
FCM
稀释度
应用 稀释度 推荐种属 FCM 1:200 Hu
CD269, also known as B-cell maturation antigen (BCMA) or tumor necrosis factor receptor superfamily member 17 (TNFRSF17), is a type III transmembrane receptor of the TNF-receptor superfamily encoded by the TNFRSF17 gene, expressed predominantly on mature B cells, plasmablasts, and plasma cells, where it binds ligands BAFF and APRIL to activate NF-κB and MAPK8/JNK pathways, thereby promoting B-cell survival, differentiation, and immunoglobulin production while playing a crucial role in autoimmune responses.
流式分析
Flow cytometric analysis of U266B1 (Human multiple myeloma B lymphocyte) labelling Human CD269 antibody at 1/200 dilution (1 μg) / (Red) compared with a Mouse IgG2a, κ (Black) Isotype control and an unlabelled control (cells without incubation with primary antibody and secondary antibody) (Blue). Goat Anti - Mouse IgG Alexa Fluor® 647 was used as the secondary antibody.
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