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宿主来源
Mouse抗原名称
CD138分子别名
Syndecan-1; SYND1; SDC; SDC1细胞定位
MembraneAccession
P18827克隆号
MI15抗体类型
Mouse mAb抗体同种型
IgG1反应种属 ?
Hu阳性样本
U266B1纯化方式
Protein G浓度
0.2 mg/ml标记
PE性状
Liquid缓冲体系
PBS, 1% BSA, 0.3% Proclin 300
储存条件
12 months from date of receipt / reconstitution, 2 to 8 °C as supplied
应用
FCM
稀释度
应用 稀释度 推荐种属 FCM 1.25μl per million cells in 100μl volume Hu
CD138, also known as syndecan-1, is a transmembrane heparan sulfate proteoglycan that plays a crucial role in cell adhesion, migration, and signaling. It is predominantly expressed on the surface of plasma cells and certain epithelial cells. In plasma cells, CD138 serves as a valuable marker for their identification and isolation, aiding in the diagnosis and study of plasma cell disorders such as multiple myomael. On epithelial cells, it contributes to the maintenance of cell structure and function by interacting with extracellular matrix components and growth factors. Additionally, CD138 is involved in various biological processes including wound healing, inflammation, and cancer progression. Its ability to bind and modulate the activity of numerous proteins makes it an important factor in cellular communication and regulation.
流式分析
Flow cytometric analysis of Human CD138 expression on U266B1 cells. Cells from the U266B1 (Human multiple myeloma B lymphocyte, Right) or Jurkat (Human T cell leukemia T lymphocyte, Left) was stained with either Phycoerythrin Mouse IgG1 Isotype Control (Black line histogram) or SDT PE Mouse Anti-Human CD138 Antibody (Red line histogram) at 1.25 μl/test. Flow cytometry and data analysis were performed using BD FACSymphony™ A1 and FlowJo™ software.







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