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Mouse Anti-Human CD243 Antibody (S-2907)

ATP-dependent translocase ABCB1,ATP-binding cassette sub-family B member 1,Multidrug resistance protein 1,P-glycoprotein 1,Phospholipid transporter ABCB1,MDR1,PGY1,ABCB1

价格 ￥600.00 （ 1-2周）
货号 S0B5635
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产品介绍

产品介绍 评论(0)

产品规格

  • 宿主来源

    Mouse

  • 抗原名称

    CD243

  • 分子别名

    ATP-dependent translocase ABCB1; ATP-binding cassette sub-family B member 1; Multidrug resistance protein 1; P-glycoprotein 1; Phospholipid transporter ABCB1; MDR1; PGY1; ABCB1

  • 细胞定位

    Cytoplasm, Cell membrane

  • Accession

    P08183

  • 克隆号

    S-2907

  • 抗体类型

    Mouse mAb

  • 抗体同种型

    IgG2a,k

  • 反应种属 ?

    Hu

  • 阳性样本

    HepG2

  • 纯化方式

    Protein A

  • 浓度

    2 mg/ml

  • 标记

    Unconjugated

  • 性状

    Liquid

  • 缓冲体系

    PBS pH7.4

  • 储存条件

    12 months from date of receipt / reconstitution, 2 to 8 °C as supplied

  • 应用

    FCM

  • 稀释度

    应用 稀释度 推荐种属
    FCM 1:200 Hu
背景介绍

  • CD243, also known as multidrug resistance protein 1 (MDR1) or P-glycoprotein (P-gp), is a 170 kDa transmembrane protein that belongs to the ATP-binding cassette (ABC) transporter family. It functions as an ATP-dependent efflux pump, transporting a wide range of lipophilic compounds, including anti-cancer drugs, out of cells. This protein is expressed on various cell types, such as B cells, T cells, and NK cells, but not on monocytes. CD243 plays a significant role in multidrug resistance in cancer therapy and is involved in the transport of molecules across cellular membranes.

  • 流式分析

    • Flow cytometric analysis of HepG2 (Human hepatocellular carcinoma epithelial cell, Left) labelling CD243 antibody at 1/200 dilution (1 μg) (Right panel) compared with a Mouse IgG2a, κ Isotype Control (Left panel) followed by Anti-Armenian Hamster IgG (H+L) biotin and Sav-PE.

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