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Alexa Fluor® 488 Rat Anti-Mouse CD186 antibody (S-R602)

C-X-C chemokine receptor type 6,CXC-R6,CXCR-6,Cxcr6

价格 ￥1,060.00 （ 供应商现货 ： 3-5个工作日）
货号 S0B5582
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产品介绍

产品介绍 评论(0)

产品规格

  • 宿主来源

    Rat

  • 抗原名称

    CD186

  • 分子别名

    C-X-C chemokine receptor type 6; CXC-R6; CXCR-6; Cxcr6

  • 细胞定位

    Cell membrane

  • Accession

    Q9EQ16

  • 克隆号

    S-R602

  • 抗体类型

    Rat mAb

  • 抗体同种型

    IgG2b,k

  • 反应种属 ?

    Ms

  • 阳性样本

    C57BL/6 mouse splenocytes

  • 纯化方式

    Protein G

  • 浓度

    0.2 mg/ml

  • 标记

    Alexa Fluor® 488

  • 性状

    Liquid

  • 缓冲体系

    PBS, 1% BSA, 0.3% Proclin 300

  • 储存条件

    12 months from date of receipt / reconstitution, 2 to 8 °C as supplied.

  • 应用

    FCM

  • 稀释度

    应用 稀释度 推荐种属
    FCM 5μl per million cells in 100μl volume Ms
背景介绍

  • CD186, also known as CXCR6, is a 39 kD G-protein coupled chemokine receptor with seven transmembrane-spanning regions. It is expressed on various immune cells, including activated and memory T cells, NKT cells, and some plasma cells. Its ligand is CXCL16, which is expressed by macrophages, dendritic cells, and liver endothelial cells. CD186 plays a role in cell migration and recruitment to inflamed sites and is also a coreceptor for HIV and SIV.

  • 流式分析

    • Flow cytometric analysis of Mouse CD186 expression on C57BL/6 mouse splenocytes. C57BL/6 mouse splenocytes were stained with Brilliant Violet 421™ Rat Anti-Mouse CD3 antibody and either Alexa Fluor® 488 Rat IgG2b, κ Isotype Control (Left panel) or SDT Alexa Fluor® 488 Rat Anti-Mouse CD186 Antibody (Right panel) at 5 μl/test. Flow cytometry and data analysis were performed using BD FACSymphony™ A1 and FlowJo™ software.

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