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宿主来源
Mouse抗原名称
CD270分子别名
Tumor necrosis factor receptor superfamily member 14; Herpes virus entry mediator A (Herpesvirus entry mediator A; HveA); Tumor necrosis factor receptor-like 2 (TR2); HVEA; HVEM; TNFRSF14细胞定位
Cell membraneAccession
Q92956克隆号
S-2915抗体类型
Mouse mAb抗体同种型
IgG1,k反应种属 ?
Hu阳性样本
Human PBMC纯化方式
Protein G浓度
2 mg/ml标记
Unconjugated性状
Liquid缓冲体系
PBS pH7.4
储存条件
12 months from date of receipt / reconstitution, 2 to 8 °C as supplied.应用
FCM
稀释度
应用 稀释度 推荐种属 FCM 1:200 Hu
CD270, also known as TNFRSF14 or Herpesvirus Entry Mediator (HVEM), is a member of the TNF-receptor superfamily. It is a type I transmembrane protein that plays a crucial role in mediating the entry of herpes simplex virus into cells through its interaction with the viral envelope glycoprotein D (gD). The cytoplasmic region of CD270 binds to several TRAF family members, which are involved in signal transduction pathways that activate the immune response . CD270 is widely expressed in various tissues, including blood vessels, brain, heart, and immune cells such as T cells and B cells . Its interactions with ligands like LIGHT (TNFSF14) and LTα are also important for immune regulation .
流式分析
Flow cytometric analysis of human PBMC (human peripheral blood mononuclear cell) labelling human CD270 antibody at 1/200 dilution (1 μg) / (Red) compared with a Mouse IgG1, κ (Black) isotype control and an unlabelled control (cells without incubation with primary antibody and secondary antibody) (Blue). Goat Anti - Mouse IgG Alexa Fluor® 647 was used as the secondary antibody.
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