Mouse Anti-Human CD122 Antibody (S-2880)
Interleukin-2 receptor subunit beta,IL-2 receptor subunit beta,IL-2R subunit beta,IL-2RB,High affinity IL-2 receptor subunit beta,Interleukin-15 receptor subunit betaImported,p70-75 (p75),IL15RB,IL2RB
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宿主来源
Mouse抗原名称
CD122分子别名
Interleukin-2 receptor subunit beta; IL-2 receptor subunit beta; IL-2R subunit beta; IL-2RB; High affinity IL-2 receptor subunit beta; Interleukin-15 receptor subunit betaImported; p70-75 (p75); IL15RB; IL2RB细胞定位
Cell membraneAccession
P14784克隆号
S-2880抗体类型
Mouse mAb抗体同种型
IgG1,k反应种属 ?
Hu阳性样本
Human Peripheral Blood cells纯化方式
Protein G浓度
2 mg/ml标记
Unconjugated性状
Liquid缓冲体系
PBS pH7.4
储存条件
12 months from date of receipt / reconstitution, 2 to 8 °C as supplied.应用
FCM
稀释度
应用 稀释度 推荐种属 FCM 1:2000 Hu
CD122, also known as the interleukin-2 receptor beta (IL-2Rβ), is a key component of the IL-2 receptor complex and plays a crucial role in regulating immune responses. It is expressed on the surface of various immune cells, including T cells and natural killer (NK) cells. CD122 is involved in mediating the effects of IL-2, which is essential for the proliferation and differentiation of T cells, as well as the maintenance of regulatory T cells (Tregs). Recent studies have shown that targeting CD122 with selective IL-2 complexes can reduce immunosuppression by Tregs and enhance antitumor immunity, making it a promising target for cancer immunotherapy.
流式分析
Flow cytometric analysis of Human Peripheral Blood cells labelling Human CD122 antibody at 1/2000 (0.1 μg) dilution/ (right panel) compared with a Mouse IgG1, κ Isotype Control / (left panel). Goat Anti-Mouse IgG Alexa Fluor® 647 was used as the secondary antibody. Then cells were stained with CD56 - Phycoerythrin antibody separately.
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