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Rat Anti-Mouse IL-2 Antibody (JES6-5H4)

Interleukin-2,T-cell growth factor (TCGF),Il-2,Il2

价格 600.00 供应商现货 : 3-5个工作日
货号 S0B5512
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产品规格
  • 宿主来源

    Rat
  • 抗原名称

    IL-2
  • 分子别名

    Interleukin-2; T-cell growth factor (TCGF); Il-2; Il2
  • 细胞定位

    Secreted
  • Accession

    P04351
  • 克隆号

    JES6-5H4
  • 抗体类型

    Rat mAb
  • 抗体同种型

    IgG2b,k
  • 反应种属 ?

    Ms
  • 纯化方式

    Protein G
  • 浓度

    2 mg/ml
  • 标记

    Unconjugated
  • 性状

    Liquid
  • 缓冲体系

    PBS pH7.4

  • 储存条件

    12 months from date of receipt / reconstitution, 2 to 8 °C as supplied.
  • 应用

    ICFCM

  • 稀释度

    应用 稀释度 推荐种属
    ICFCM 1:200 Ms
背景介绍
  • Interleukin-2 (IL-2) is a cytokine that plays a crucial role in the immune system. It is primarily produced by activated T cells and has multiple functions. IL-2 promotes the proliferation and differentiation of T cells, enhancing their ability to fight infections and tumors. It also stimulates the growth and activity of natural killer (NK) cells, which are important for immune defense. Additionally, IL-2 can regulate the activity of regulatory T cells (Tregs), helping to maintain immune tolerance and prevent autoimmune diseases. In clinical settings, IL-2 has been used to treat certain cancers by boosting the immune response, although its use is limited due to potential side effects. Its discovery and research have significantly advanced our understanding of the immune system and provided new strategies for immunotherapy.

  • 流式分析

    • Flow cytometric analysis of 4% PFA fixed 0.1% Tween-20 permeabilized Mouse splenocytes, treated 6h with 80nM PMA, 1.34μM Ionomycin and 10.6μM Brefeldin A and 2μM Monensin (Right Panel) or untreated (Left Panel), labeling IL-2 at 1/200 dilution (1 μg). Goat Anti - Rat IgG Alexa Fluor® 488 was used as the secondary antibody. Then cells were stained with PE Rat Anti-Mouse CD3 Antibody (S0B1697) separately.

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