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Rat抗原名称
CD107b (Mac-3)分子别名
Lysosome-associated membrane glycoprotein 2; LAMP-2; Lysosome-associated membrane protein 2; CD107 antigen-like family member B; Lysosomal membrane glycoprotein type B (LGP-B); CD107b; Lamp2细胞定位
Cell membraneAccession
P17047克隆号
M3/84抗体类型
Rat mAb抗体同种型
IgG1,k反应种属 ?
Ms阳性样本
BALB/c mouse peritoneal exudates cells纯化方式
Protein G浓度
2 mg/ml标记
Unconjugated性状
Liquid缓冲体系
PBS pH7.4
储存条件
12 months from date of receipt / reconstitution, 2 to 8 °C as supplied.应用
FCM
稀释度
应用 稀释度 推荐种属 FCM 1:200 Ms
CD107b, also known as lysosome-associated membrane protein 2 (LAMP-2), is a highly glycosylated type I transmembrane protein with a molecular weight of approximately 105–120 kDa. It is primarily located in the lysosomal/endosomal membranes of nearly all cells and can be transiently expressed on the surface of activated platelets, activated lymphocytes, and some tumor cell lines. LAMP-2 plays crucial roles in various cellular processes, including cell adhesion, cellular homeostasis, autophagocytosis, antigen presentation, and protection of the lysosome. Additionally, it may be involved in tumor cell metastasis by mediating adhesion to vascular endothelium.
流式分析
Flow cytometric analysis of BALB/c mouse peritoneal exudates cells labelling Mouse CD107b (Mac-3) antibody at 1/200 dilution (1 μg) / (Right panel) compared with a Rat IgG1, κ Isotype Control / (Left panel). Goat Anti-Rat IgG Alexa Fluor® 488 was used as the secondary antibody. Then cells were stained with CD11b - Brilliant Violet 421™ Antibody separately.
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