Alexa Fluor® 647 Rat Anti-Mouse CD107b (Mac-3) Antibody (M3/84)
Lysosome-associated membrane glycoprotein 2,LAMP-2,Lysosome-associated membrane protein 2,CD107 antigen-like family member B,Lysosomal membrane glycoprotein type B (LGP-B),Lamp2
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宿主来源
Rat抗原名称
CD107b分子别名
Lysosome-associated membrane glycoprotein 2; LAMP-2; Lysosome-associated membrane protein 2; CD107 antigen-like family member B; Lysosomal membrane glycoprotein type B (LGP-B); Lamp2细胞定位
Lysosome, Endosome, Cell membraneAccession
P17047克隆号
M3/84抗体类型
Rat mAb抗体同种型
IgG1,k反应种属 ?
Ms阳性样本
BALB/c mouse peritoneal exudates cells纯化方式
Protein G浓度
0.05mg/ml标记
Alexa Fluor® 647性状
Liquid缓冲体系
PBS, 1% BSA, 0.3% Proclin 300储存条件
12 months from date of receipt / reconstitution, 2 to 8 °C as supplied.应用
FCM
稀释度
应用 稀释度 推荐种属 FCM 5μl per million cells in 100μl volume Ms
CD107b, also known as lysosome-associated membrane protein 2 (LAMP-2), is a highly glycosylated type I transmembrane protein with a molecular weight of approximately 105–120 kDa. It is primarily located in the lysosomal/endosomal membranes of nearly all cells and can be transiently expressed on the surface of activated platelets, activated lymphocytes, and some tumor cell lines. LAMP-2 plays crucial roles in various cellular processes, including cell adhesion, cellular homeostasis, autophagocytosis, antigen presentation, and protection of the lysosome. Additionally, it may be involved in tumor cell metastasis by mediating adhesion to vascular endothelium.
流式分析
Flow cytometric analysis of Mouse CD107b (Mac-3) expression on BALB/c mouse peritoneal exudates cells. BALB/c mouse peritoneal exudates cells were stained with SDT Brilliant Violet 421™ Rat Anti-Mouse CD11b Antibody and either Alexa Fluor® 647 Rat IgG1, κ Isotype Control (Left panel) or SDT Alexa Fluor® 647 Rat Anti-Mouse CD107 (Mac-3) Antibody (Right panel) at 5 μl/test. Flow cytometry and data analysis were performed using BD FACSymphony™ A1 and FlowJo™ software.
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