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Pacific Blue Rabbit Anti-Mouse NK1.1/CD161 Antibody (S-428-32)

Killer cell lectin-like receptor subfamily B member 1C,CD161 antigen-like family member C,Lymphocyte antigen 55c (Ly-55c),NK1.1,NKR-P1.9,NKR-P1C,Natural killer cell surface protein P1-40 (NKR-P1 40),CD161c,Ly55c,Nkrp1c,Klrb1c

价格 ￥880.00 （ 供应商现货 ： 3-5个工作日）
货号 S0B5495
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产品介绍

产品介绍 评论(0)

产品规格

  • 宿主来源

    Rabbit

  • 抗原名称

    NK1.1/CD161

  • 分子别名

    Killer cell lectin-like receptor subfamily B member 1C; CD161 antigen-like family member C; Lymphocyte antigen 55c (Ly-55c); NK1.1; NKR-P1.9; NKR-P1C; Natural killer cell surface protein P1-40 (NKR-P1 40); CD161c; Ly55c; Nkrp1c; Klrb1c

  • 免疫原

    Recombinant Protein

  • 细胞定位

    Membrane

  • Accession

    P27814

  • 克隆号

    S-428-32

  • 抗体类型

    Recombinant mAb

  • 抗体同种型

    IgG

  • 反应种属 ?

    Ms

  • 阳性样本

    C57BL/6 mouse splenocytes

  • 纯化方式

    Protein A

  • 浓度

    0.2 mg/ml

  • 标记

    Pacific Blue

  • 性状

    Liquid

  • 缓冲体系

    PBS, 1% BSA, 0.3% Proclin 300

  • 储存条件

    12 months from date of receipt / reconstitution, 2 to 8 °C as supplied.

  • 应用

    FCM

  • 稀释度

    应用 稀释度 推荐种属
    FCM 1.25μl per million cells in 100μl volume Ms
背景介绍

  • NK1.1/CD161, also known as KLRB1, is a receptor protein expressed on the surface of natural killer (NK) cells and certain T cells. In mice, NK1.1 belongs to the NKRP1 receptor family and interacts with C-type lectin-related molecules, playing a role in immune recognition and regulation. In humans, CD161 on NK cells interacts with ligands such as LLT1, and this interaction is inhibitory, helping to regulate NK cell function. Additionally, CD161 is involved in intracellular signaling pathways, such as the AKT pathway, which influences NK cell activity. This protein is also a marker for different subsets of NK cells, with high expression in certain mature and cytotoxic NK cell populations.

  • 流式分析

    • Flow cytometric analysis of Mouse NK1.1/CD161 expression on C57BL/6 mouse splenocytes. C57BL/6 mouse splenocytes were stained with FITC Rat Anti-Mouse CD49b antibody and either Pacific Blue Rabbit IgG Isotype Control (Left panel) or SDT Pacific Blue Rabbit Anti-Mouse NK1.1/CD161 antibody (Right panel) at 1.25 μl/test. Flow cytometry and data analysis were performed using BD FACSymphony™ A1 and FlowJo™ software.

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