PE Mouse Anti-Human CD62P Antibody (S-921-3)
P-selectin,CD62 antigen-like family member P,Granule membrane protein 140 (GMP-140),Leukocyte-endothelial cell adhesion molecule 3 (LECAM3),Platelet activation dependent granule-external membrane protein (PADGEM),GMRP,GRMP,SELP
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宿主来源
Mouse抗原名称
CD62P分子别名
P-selectin; CD62 antigen-like family member P; Granule membrane protein 140 (GMP-140); Leukocyte-endothelial cell adhesion molecule 3 (LECAM3); Platelet activation dependent granule-external membrane protein (PADGEM); GMRP; GRMP; SELP免疫原
Recombinant Protein细胞定位
Cell membraneAccession
P16109克隆号
S-921-3抗体类型
Mouse mAb抗体同种型
IgG1,k反应种属 ?
Hu阳性样本
human PBMC纯化方式
Protein G浓度
0.05mg/ml标记
PE性状
Liquid缓冲体系
PBS, 1% BSA, 0.3% Proclin 300
储存条件
12 months from date of receipt / reconstitution, 2 to 8 °C as supplied.
应用
FCM
稀释度
应用 稀释度 推荐种属 FCM 5μl per million cells in 100μl volume Hu
CD62P, also known as P-selectin, is a 140 kDa type I transmembrane glycoprotein that plays a crucial role in cell adhesion and immune responses. It is stored in α-granules of platelets and Weibel-Palade bodies of endothelial cells, and is rapidly relocated to the cell surface upon activation by stimuli such as thrombin or histamine. CD62P mediates the initial adhesion and rolling of leukocytes on endothelial cells during inflammation and facilitates interactions between activated platelets and neutrophils or monocytes. It binds to specific carbohydrate ligands on leukocytes in a calcium-dependent manner. Additionally, CD62P is used as a marker for platelet activation and has potential diagnostic value in various diseases.
流式分析
Flow cytometric analysis of Human CD62P expression on human PBMC (human peripheral blood mononuclear cells). Human PBMC were stained with Allophycocyanin Mouse Anti-Human CD41 Antibody at 5 μl/test and either PE Mouse IgG1, κ Isotype Control (Left panel) or SDT PE Mouse Anti-Human CD62P Antibody (Right panel) at 5 μl/test. Flow cytometry and data analysis were performed using BD FACSymphony™ A1 and FlowJo™ software.
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