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宿主来源
Mouse抗原名称
CD2分子别名
T-cell surface antigen CD2; Erythrocyte receptor; LFA-2; LFA-3 receptor; Rosette receptor; T-cell surface antigen T11/Leu-5; SRBC免疫原
Recombinant Protein细胞定位
Cell membraneAccession
P06729克隆号
S-633-25抗体类型
Mouse mAb抗体同种型
IgG1,k反应种属 ?
Hu阳性样本
Human Peripheral Blood cells纯化方式
Protein G浓度
0.05mg/ml标记
FITC性状
Liquid缓冲体系
PBS, 1% BSA, 0.3% Proclin 300
储存条件
12 months from date of receipt / reconstitution, 2 to 8 °C as supplied.
应用
FCM
稀释度
应用 稀释度 推荐种属 FCM 5μl per million cells in 100μl volume Hu
CD2, also known as the T-cell surface antigen CD2, is a transmembrane glycoprotein primarily expressed on the surface of T cells and natural killer (NK) cells. It belongs to the immunoglobulin superfamily and plays a crucial role in mediating cell adhesion and activation. CD2's principal ligand is CD58 (LFA-3), which is expressed on antigen-presenting cells and other immune cells. The interaction between CD2 and CD58 facilitates T-cell activation and enhances the immune response. Structurally, CD2 consists of an extracellular domain responsible for ligand binding, a transmembrane domain anchoring it to the cell membrane, and an intracellular domain involved in signal transduction.
流式分析
Flow cytometric analysis of Human CD2 expression on Human Peripheral Blood cells. Human Peripheral Blood cells were stained with Brilliant Violet 421™ Mouse Anti-Human CD3 Antibody and either Mouse IgG1, κ Isotype Control (Left panel) or SDT FITC Mouse Anti-Human CD2 Antibody (Right panel) at 5 μl/test. Flow cytometry and data analysis were performed using BD FACSymphony™ A1 and FlowJo™ software.
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