分享产品介绍 评论(0)
宿主来源
Mouse抗原名称
CD71分子别名
Transferrin receptor protein 1; TR; TfR; TfR1; Trfr; Tfrc细胞定位
Cell membraneAccession
Q99376克隆号
OX-26抗体类型
Mouse mAb抗体同种型
IgG2a,k反应种属 ?
Rt阳性样本
SD Rat bone marrow纯化方式
Protein A浓度
0.05mg/ml标记
Alexa Fluor® 647性状
Liquid缓冲体系
PBS, 1% BSA, 0.3% Proclin 300
储存条件
12 months from date of receipt / reconstitution, 2 to 8 °C as supplied.
应用
FCM
稀释度
应用 稀释度 推荐种属 FCM 5μl per million cells in 100μl volume Rt
CD71, also known as transferrin receptor 1 (TfR1), is a type II transmembrane glycoprotein that exists as a disulfide-linked homodimer on the cell surface. It plays a crucial role in cellular iron uptake by binding to iron-bound transferrin and mediating its internalization through receptor-mediated endocytosis. CD71 is widely expressed on proliferating cells, including erythroid precursors, activated immune cells, and various cancer cells. It is also a preferred entry receptor for several viruses, such as arenaviruses and hepatitis C virus. In addition, CD71 has been identified as a marker for cell proliferation and activation, and its expression is often used in the diagnosis and prognosis of hematological diseases.
流式分析
Flow cytometric analysis of Rat CD71 expression on SD Rat bone marrow. SD Rat bone marrow was stained with Alexa Fluor® 647 Mouse IgG2a, κ Isotype Control (Black line histogram) or SDT Alexa Fluor® 647 Mouse Anti-Rat CD71 Antibody (Red line histogram) at 5 μl/test, cells without incubation with primary antibody and secondary antibody (Blue line histogram) was used as unlabelled control. Flow cytometry and data analysis were performed using BD FACSymphony™ A1 and FlowJo™ software.
评论(0)