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宿主来源
Armenian hamster抗原名称
CD29分子别名
Integrin beta-1; Fibronectin receptor subunit beta; VLA-4 subunit beta; Itgb1细胞定位
Cell membraneAccession
P09055克隆号
HMB1-1抗体类型
Recombinant mAb抗体同种型
IgG反应种属 ?
Ms阳性样本
BALB/c mouse bone marrow纯化方式
Protein G浓度
2 mg/ml标记
Unconjugated性状
Liquid缓冲体系
PBS pH7.4
储存条件
12 months from date of receipt / reconstitution, 2 to 8 °C as supplied.
应用
FCM
稀释度
应用 稀释度 推荐种属 FCM 1:100 Ms, Rt
CD29, also known as integrin beta-1 (ITGB1), is a crucial cell surface receptor involved in cell adhesion, migration, and signaling. It is a member of the integrin family and is encoded by the ITGB1 gene, located on human chromosome 10p11.2. CD29 forms complexes with various integrin alpha subunits to interact with extracellular matrix (ECM) proteins such as collagen, laminin, and fibronectin. This protein plays a significant role in cellular processes including “inside-out” and “outside-in” signaling pathways, which are essential for cell survival and metastasis. Additionally, CD29 is highly expressed in various cell types and is implicated in multiple diseases, including cancer progression and immune regulation.
流式分析
Flow cytometric analysis of BALB/c mouse bone marrow labelling CD29 Antibody at 1/100 dilution (2 μg) / (Right panel) compared with a Armenian hamster IgG Isotype Control / (Left panel). Goat Anti-Armenian hamster IgG Alexa Fluor® 488 was used as the secondary antibody. Then cells were stained with CD45R/B220 - Alexa Fluor® 647 Antibody separately.
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