Rat Anti-Mouse CD140a Antibody (S-R682)
Platelet-derived growth factor receptor alpha,PDGF-R-alpha,PDGFR-alpha,Alpha platelet-derived growth factor receptor,Alpha-type platelet-derived growth factor receptor,CD140 antigen-like family member A,Platelet-derived growth factor alpha receptor,Pdgfra
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宿主来源
Rat抗原名称
CD140a分子别名
Platelet-derived growth factor receptor alpha; PDGF-R-alpha; PDGFR-alpha; Alpha platelet-derived growth factor receptor; Alpha-type platelet-derived growth factor receptor; CD140 antigen-like family member A; Platelet-derived growth factor alpha receptor; Pdgfra细胞定位
Cell membraneAccession
P26618克隆号
S-R682抗体类型
Rat mAb抗体同种型
IgG2a,k反应种属 ?
Ms阳性样本
NIH/3T3纯化方式
Protein G浓度
2 mg/ml标记
Unconjugated性状
Liquid缓冲体系
PBS pH7.4
储存条件
12 months from date of receipt / reconstitution, 2 to 8 °C as supplied.
应用
FCM
稀释度
应用 稀释度 推荐种属 FCM 1:2000 Ms
CD140a, also known as Platelet-Derived Growth Factor Receptor Alpha (PDGFRα), is a cell surface receptor tyrosine kinase that plays a crucial role in various biological processes. It is a member of the receptor tyrosine kinase (RTK) III class and is widely expressed in cells of mesenchymal origin, including fibroblasts, endothelial cells, glial cells, and certain tumor cells. CD140a binds to various isoforms of platelet-derived growth factors (PDGFs) such as PDGF-AA, PDGF-AB, and PDGF-BB, forming homodimers or heterodimers with CD140b (PDGFRβ) to mediate cellular responses. This receptor is involved in cell proliferation, differentiation, migration, and survival, and is essential for embryonic development, wound healing, and the regulation of platelet activation.
流式分析
Flow cytometric analysis of NIH/3T3 (Mouse embryonic fibroblast) labelling Mouse CD140a antibody at 1/2000 dilution (0.1 μg) / (Red) compared with a Rat IgG2a, κ (Black) Isotype control and an unlabelled control (cells without incubation with primary antibody and secondary antibody) (Blue). Goat Anti - Rat IgG Alexa Fluor® 647 was used as the secondary antibody.
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