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宿主来源
Syrian Hamster抗原名称
Podoplanin分子别名
Glycoprotein 38; OTS-8; PA2.26 antigen; Transmembrane glycoprotein E11; Gp38; Ots8; Pdpn细胞定位
Cell membraneAccession
Q62011克隆号
S-R689抗体类型
Recombinant mAb抗体同种型
IgG反应种属 ?
Ms阳性样本
C2C12. Cells纯化方式
Protein G浓度
0.05mg/ml标记
FITC性状
Liquid缓冲体系
PBS, 1% BSA, 0.3% Proclin 300储存条件
12 months from date of receipt / reconstitution, 2 to 8 °C as supplied.应用
FCM
稀释度
应用 稀释度 推荐种属 FCM 5μl per million cells in 100μl volume Ms
Podoplanin is a small, mucin-like transmembrane glycoprotein that plays diverse roles in both physiological and pathological processes. Initially identified in podocytes of the kidney, it is also expressed in various tissues, including the brain, heart, lungs, and lymphatic endothelium. Podoplanin is a key marker for lymphatic vessels and is involved in lymphangiogenesis, embryonic development, and platelet aggregation. In cancer, its expression is associated with tumor invasion and metastasis, making it a potential therapeutic target. Additionally, podoplanin has been implicated in neurological disorders, inflammation, and immune responses, highlighting its multifaceted importance in health and disease.
流式分析
Flow cytometric analysis of Mouse Podoplanin expression on C2C12. Cells from the C2C12 (Mouse myoblasts myoblast, Right) or RAW 264.7 (Mouse Abelson murine leukemia virus-induced tumor macrophage, Left) was stained with either FITC Syrian hamster IgG Isotype Control (Black line histogram) or SDT FITC Syrian hamster Anti-Mouse Podoplanin Antibody (Red line histogram) at 5μl/test, cells without incubation with primary antibody and secondary antibody (Blue line histogram) was used as unlabelled control. Flow cytometry and data analysis were performed using BD FACSymphony™ A1 and FlowJo™ software.
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