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宿主来源
Rat抗原名称
CD205分子别名
Lymphocyte antigen 75; Ly-75; DEC-205; Ly75细胞定位
MembraneAccession
Q60767克隆号
NLDC-145抗体类型
Rat mAb抗体同种型
IgG2a,k反应种属 ?
Ms阳性样本
BALB/c mouse bone marrow纯化方式
Protein G浓度
0.2mg/ml标记
Alexa Fluor® 647性状
Liquid缓冲体系
PBS, 1% BSA, 0.3% Proclin 300
储存条件
12 months from date of receipt / reconstitution, 2 to 8 °C as supplied.
应用
FCM
稀释度
应用 稀释度 推荐种属 FCM 1.25μl per million cells in 100μl volume Ms
CD205, also known as DEC-205, is a type I C-type lectin receptor and a member of the macrophage mannose receptor family. It is primarily expressed on dendritic cells (DCs), cortical thymic epithelial cells, and some leukocyte sub-populations. This receptor is involved in antigen uptake, processing, and presentation, playing a crucial role in the immune system. CD205 has a unique pH-dependent conformational change, allowing it to efficiently capture and internalize antigens in an acidic environment. Due to its high antigen-presenting efficiency, CD205 is widely used in immunotherapy, particularly in the development of antiviral and antitumor vaccines.
流式分析
Flow cytometric analysis of Mouse CD205 expression on BALB/c mouse bone marrow. BALB/c mouse bone marrow was stained with Pacific Blue™ Rat Anti-Mouse Ly-6G/Ly-6C Antibody and either Alexa Fluor® 647 Rat IgG2a, κ Isotype Control (Left panel) or SDT Alexa Fluor® 647 Rat Anti-Mouse CD205 Antibody (Right panel) at 1.25μl/test. Flow cytometry and data analysis were performed using BD FACSymphony™ A1 and FlowJo™ software.
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