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宿主来源
Mouse抗原名称
CD7分子别名
T-cell antigen CD7; GP40; T-cell leukemia antigen; T-cell surface antigen Leu-9; TP41免疫原
Recombinant Protein细胞定位
Cell membraneAccession
P09564克隆号
S-575-17抗体类型
Mouse mAb抗体同种型
IgG1,k反应种属 ?
Hu阳性样本
human peripheral blood cells纯化方式
Protein G浓度
0.2 mg/ml标记
Pacific Blue性状
Liquid缓冲体系
PBS, 1% BSA, 0.3% Proclin 300储存条件
12 months from date of receipt / reconstitution, 2 to 8 °C as supplied.
应用
FCM
稀释度
应用 稀释度 推荐种属 FCM 1.25μl per million cells in 100μl volume Hu
CD7, also known as GP40 or T-cell antigen CD7, is a 40 kDa transmembrane glycoprotein that belongs to the immunoglobulin superfamily. It is encoded by the CD7 gene located on chromosome 17 and is expressed on the surface of T cells, natural killer (NK) cells, and their precursors. CD7 plays a crucial role in immune regulation by participating in T-cell activation, providing co-stimulatory signals, and facilitating cell adhesion. It is one of the earliest antigens to appear on T-lymphocyte lineage cells and is highly expressed in various stages of T, B, and myeloid cell differentiation. Additionally, CD7 is involved in T-cell infiltration in tumors, making it an important target for cancer immunotherapy.
流式分析
Flow cytometric analysis of Human CD7 expression on human peripheral blood cells. Human peripheral blood cells were stained with Alexa Fluor® 647 Mouse Anti-Human CD3 Antibody and either Pacific Blue Mouse IgG1, κ Isotype Control (Left panel) or SDT Pacific Blue Mouse Anti-Human CD7 Antibody (Right panel) at 1.25μl/test. Flow cytometry and data analysis were performed using BD FACSymphony™ A1 and FlowJo™ software.
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