APC Mouse Anti-Human CD59 Antibody (S-R567)
CD59 glycoprotein,1F5 antigen,20 kDa homologous restriction factor (HRF-20,HRF20),MAC-inhibitory protein (MAC-IP),MEM43 antigen,Membrane attack complex inhibition factor (MACIF),Membrane inhibitor of reactive lysis (MIRL),Protectin,MIC11,MIN1,MIN2,MIN3,MSK21
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宿主来源
Mouse抗原名称
CD59分子别名
CD59 glycoprotein; 1F5 antigen; 20 kDa homologous restriction factor (HRF-20; HRF20); MAC-inhibitory protein (MAC-IP); MEM43 antigen; Membrane attack complex inhibition factor (MACIF); Membrane inhibitor of reactive lysis (MIRL); Protectin; MIC11; MIN1; MIN2; MIN3; MSK21细胞定位
Secreted, Cell membraneAccession
P13987克隆号
S-R567抗体类型
Mouse mAb抗体同种型
IgG2a反应种属 ?
Hu阳性样本
human peripheral blood cells纯化方式
Protein A浓度
0.2 mg/ml标记
APC性状
Liquid缓冲体系
PBS, 1% BSA, 0.3% Proclin 300
储存条件
12 months from date of receipt / reconstitution, 2 to 8 °C as supplied.应用
FCM
稀释度
应用 稀释度 推荐种属 FCM 5μl per million cells in 100μl volume Hu
CD59, also known as membrane inhibitor of reactive lysis (MIRL) or protectin, is a glycosylphosphatidylinositol (GPI)-anchored membrane protein that plays a crucial role in regulating the complement system, an essential part of the innate immune response. It is widely expressed on various human cells and tissues, including erythrocytes, leukocytes, fibroblasts, and epithelial cells. The primary function of CD59 is to inhibit the formation of the membrane attack complex (MAC), thereby preventing complement-mediated cell lysis. This protective mechanism is vital for maintaining cell integrity and preventing excessive immune-mediated damage.
流式分析
Flow cytometric analysis of Human CD59 expression on human peripheral blood cells. Human peripheral blood cells were stained with either APC Mouse IgG2a Isotype Control (Black line histogram) or SDT APC Mouse Anti-Human CD59 Antibody (Red line histogram) at 5μl/test, cells without incubation with primary antibody and secondary antibody (Blue line histogram) was used as unlabelled control. Flow cytometry and data analysis were performed using BD FACSymphony™ A1 and FlowJo™ software.
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