Rat Anti-Mouse CD184 Antibody (S-R670)
C-X-C chemokine receptor type 4,CXC-R4,CXCR-4,Fusin,Leukocyte-derived seven transmembrane domain receptor (LESTR),Pre-B-cell-derived chemokine receptor (PB-CKR),Stromal cell-derived factor 1 receptor (SDF-1 receptor),Cmkar4,Lestr,Sdf1r,Cxcr4
货号: S0B5104
- 价格: ¥600
- 规格:
- 数量:
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宿主来源
Rat抗原名称
CD184分子别名
C-X-C chemokine receptor type 4; CXC-R4; CXCR-4; Fusin; Leukocyte-derived seven transmembrane domain receptor (LESTR); Pre-B-cell-derived chemokine receptor (PB-CKR); Stromal cell-derived factor 1 receptor (SDF-1 receptor); Cmkar4; Lestr; Sdf1r; Cxcr4细胞定位
Cell membrane, Cell junction, LysosomeAccession
P70658克隆号
S-R670抗体类型
Rat mAb抗体同种型
IgG2b,k应用
FCM反应种属 ?
Ms阳性样本
C57BL/6 mouse thymocytes纯化方式
Protein G浓度
2 mg/ml标记
Unconjugated性状
Liquid缓冲体系
PBS pH7.4
储存条件
12 months from date of receipt / reconstitution, 2 to 8 °C as supplied.
应用 | 稀释度 | 推荐种属 |
---|---|---|
FCM | 1μg per million cells in 100μl volume | Ms |
CD184, also known as CXCR4 or Fusin, is a seven-transmembrane G protein-coupled receptor that plays a crucial role in various physiological processes. It is widely expressed on hematopoietic cells, including lymphoid and myeloid precursor cells, megakaryocytes, and endothelial cells. Its natural ligand is stromal cell-derived factor-1 (SDF-1), a C-X-C chemokine that induces chemotaxis and enhances intracellular signaling through calcium ion influx and MAPK activation.
流式分析
Flow cytometric analysis of C57BL/6 mouse thymocytes labelling Mouse CD184 antibody at 1/200 (1 μg) dilution/ (Right panel) compared with a Rat IgG2b, κ Isotype Control / (Left panel). Goat Anti-Rat IgG Alexa Fluor® 647 was used as the secondary antibody. Then cells were stained with CD4 - Brilliant Violet 421™ Antibody separately.
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