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Mouse Anti-Human CD303 Antibody (S-R662)

C-type lectin domain family 4 member C,Blood dendritic cell antigen 2 (BDCA-2),C-type lectin superfamily member 7,Dendritic lectin,BDCA2,CLECSF11,CLECSF7,DLEC,HECL,CLEC4C

价格 ￥600.00 （ 供应商现货 ： 3-5个工作日）
货号 S0B5097
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产品介绍

产品介绍 评论(0)

产品规格

  • 宿主来源

    Mouse

  • 抗原名称

    CD303

  • 分子别名

    C-type lectin domain family 4 member C; Blood dendritic cell antigen 2 (BDCA-2); C-type lectin superfamily member 7; Dendritic lectin; BDCA2; CLECSF11; CLECSF7; DLEC; HECL; CLEC4C

  • 细胞定位

    Cell membrane

  • Accession

    Q8WTT0

  • 克隆号

    S-R662

  • 抗体类型

    Mouse mAb

  • 抗体同种型

    IgG2a,k

  • 反应种属 ?

    Hu

  • 阳性样本

    human PBMC

  • 纯化方式

    Protein A

  • 浓度

    2 mg/ml

  • 标记

    Unconjugated

  • 性状

    Liquid

  • 缓冲体系

    PBS pH7.4

  • 储存条件

    12 months from date of receipt / reconstitution, 2 to 8 °C as supplied.

  • 应用

    FCM

  • 稀释度

    应用 稀释度 推荐种属
    FCM 1:200 Hu
背景介绍

  • CD303, also known as BDCA-2 or CLEC4C, is a 38 kD type II transmembrane glycoprotein and a member of the C-type lectin superfamily. It is specifically expressed on plasmacytoid dendritic cells (pDCs) and plays a crucial role in antigen capture and processing, as well as in cell adhesion and signaling. CD303 is involved in the presentation of antigens to T cells and can mediate the inhibition of IFN-α/β expression in pDCs when cross-linked. This molecule is also a potential therapeutic target in diseases such as systemic lupus erythematosus due to its role in immune regulation.

  • 流式分析

    • Flow cytometric analysis of human PBMC (human peripheral blood mononuclear cells) labelling Human CD303 antibody at 1/200 (1 μg) dilution/ (Right panel) compared with a Mouse IgG2a, κ Isotype Control / (Left panel). Goat Anti-Mouse IgG Alexa Fluor® 488 was used as the secondary antibody. Then cells were stained with CD123 - PE/Cy7 Antibody separately.

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