Rat Anti-Mouse CD117 Antibody (S-R681)
CD117,KIT,C-Kit,PBT,Piebald trait protein,Proto-oncogene c-Kit,Tyrosine-protein kinase Kit,p145 c-kit,v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog,SCFR,Mast/stem cell growth factor receptor Kit,Kit,Sl
货号： S0B5077
- 价格： ￥600
- 规格：
- 数量：
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宿主来源
Rat抗原名称
Mouse CD117分子别名
Mast/stem cell growth factor receptor Kit; SCFR; Proto-oncogene c-Kit; Tyrosine-protein kinase Kit; Kit; Sl细胞定位
Cell membraneAccession
P05532克隆号
S-R681抗体类型
Rat mAb抗体同种型
IgG2b,k应用
FCM反应种属 ?
Ms阳性样本
C57BL/6 mouse bone marrow纯化方式
Protein G浓度
2 mg/ml标记
Unconjugated性状
Liquid缓冲体系
PBS pH7.4
储存条件
12 months from date of receipt / reconstitution, 2-8 °C as supplied.
| 应用 | 稀释度 | 推荐种属 |
|---|---|---|
| FCM | 1:200 | Ms |
CD117, also known as c-Kit, is a receptor tyrosine kinase involved in cell growth, survival, and differentiation. It is expressed on various cell types, including hematopoietic stem cells, mast cells, melanocytes, and interstitial cells of Cajal in the gastrointestinal tract. CD117 plays a critical role in normal development and immune function, and its dysregulation is associated with several diseases, including cancers such as gastrointestinal stromal tumors (GIST) and acute myeloid leukemia (AML). Additionally, CD117 is a marker for cancer stem cells in some solid tumors and is targeted in cancer therapies.
流式分析
Flow cytometric analysis of C57BL/6 mouse bone marrow labelling Mouse CD117 antibody at 1/200 (1 μg) dilution/ (Right panel) compared with a Rat IgG2b, κ Isotype Control / (Left panel). Goat Anti-Rat IgG Alexa Fluor® 647 was used as the secondary antibody. Then cells were stained with CD11b - Brilliant Violet 421™ Antibody separately.
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