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宿主来源
Mouse抗原名称
HLA-ABC分子别名
HLA class I histocompatibility antigen; A alpha chain; Human leukocyte antigen A (HLA-A); HLA class I histocompatibility antigen; B alpha chain; Human leukocyte antigen B (HLA-B); HLA class I histocompatibility antigen, C alpha chain; HLA-Cw; Human leukocyte antigen C细胞定位
Cell membraneAccession
P04439, P01889, P10321克隆号
S-R526抗体类型
Mouse mAb抗体同种型
IgG2a,k应用
FCM反应种属 ?
Hu阳性样本
human peripheral blood纯化方式
Protein A浓度
0.2 mg/ml标记
FITC性状
Liquid缓冲体系
PBS, 25% Glycerol, 1% BSA, 0.3% Proclin 300
储存条件
12 months from date of receipt / reconstitution, 2 to 8 °C as supplied.
| 应用 | 稀释度 | 推荐种属 |
|---|---|---|
| FCM | 1.25μl per million cells in 100μl volume | Hu |
HLA-A, B, and C are part of the Human Leukocyte Antigen (HLA) system, which is the human version of the Major Histocompatibility Complex (MHC). HLA-A, B, and C are classic Class I molecules of the HLA system, expressed on the surface of all nucleated cells. They are responsible for presenting endogenous antigens, such as those produced by viruses or tumor cells, to CD8+ T cells, thereby activating cellular immune responses. These molecules consist of a heavy chain and a light chain (β2-microglobulin), with the heavy chain encoded by the HLA-A, B, and C genes. In medical research, the expression of HLA-A, B, and C has been studied in various diseases, especially in tumor immunology. Research on HLA-A, B, and C also includes the frequency and clinical significance of their haplotypes in haplotype transplantation. Studying the frequency of these haplotypes is valuable for selecting the best donors and unrelated donors, particularly when performing related HLA haplotype transplantations.
流式分析
Flow cytometric analysis of Human HLA-ABC expression on human peripheral blood. Human peripheral blood was stained with FITC Mouse IgG2a, κ Isotype Control (Black line histogram) and SDT FITC Mouse Anti-Human HLA-ABC (Red line histogram) at 1.25μl/test. Flow cytometry and data analysis were performed using BD FACSymphony™ A1 and FlowJo™ software.
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