分享产品介绍 评论(0)
宿主来源
Mouse抗原名称
CD3d分子别名
T-cell surface glycoprotein CD3 delta chain; T-cell receptor T3 delta chain; T3D细胞定位
Cell membraneAccession
P04234克隆号
MEM-57抗体类型
Mouse mAb抗体同种型
IgG2a反应种属 ?
Hu阳性样本
human PBMC纯化方式
Protein A浓度
0.2 mg/ml标记
Biotin性状
Liquid缓冲体系
PBS pH7.4, 0.03% Proclin 300
储存条件
12 months from date of receipt / reconstitution, 2 to 8 °C as supplied.
应用
FCM
稀释度
应用 稀释度 推荐种属 FCM 5μl per million cells in 100μl volume Hu
CD3d, also known as CD3 delta chain, is a protein-coding gene located on chromosome 11q23.3. The protein encoded by CD3D is a single-pass type I membrane protein and is a component of the T-cell receptor (TCR) complex, which is crucial for T-cell development and signaling. It forms part of the CD3 complex along with other subunits like CD3γ, CD3ε, and CD3ζ, and it interacts with either the TCRα/β or TCRγ/δ heterodimer to form the TCR/CD3 complex on the T-cell surface. The CD3d protein is also a target for immunotherapies. For example, bispecific antibodies that target CD3d along with tumor-associated antigens can redirect T cells to attack cancer cells, making it a promising target for cancer immunotherapy.
流式分析
Flow cytometric analysis of Human CD3d expression on human PBMC (human peripheral blood mononuclear cells). Human PBMC were stained with Brilliant Violet 421™ Mouse Anti-Human CD19 antibody and either Biotin Isotype Control (Left panel) or SDT Biotin Mouse Anti-Human CD3d Antibody (Right panel) at 5μl/test followed by Sav-iFluor 488. Flow cytometry and data analysis were performed using BD FACSymphony™ A1 and FlowJo™ software.
评论(0)