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Alexa Fluor® 647 Rat Anti-Mouse CD184 Antibody (S-R670)

C-X-C chemokine receptor type 4,CXC-R4,CXCR-4,Fusin,Leukocyte-derived seven transmembrane domain receptor (LESTR),Pre-B-cell-derived chemokine receptor (PB-CKR),Stromal cell-derived factor 1 receptor (SDF-1 receptor),Cxcr4,Cmkar4,Lestr,Sdf1r

货号： S0B5054

Datasheet COA
  • 价格： ￥300
  • 规格：
  • 数量：
斯达特大包装询价 大包装询价

产品介绍 评论(0)

产品规格

  • 宿主来源

    Rat

  • 抗原名称

    Mouse CD184

  • 分子别名

    C-X-C chemokine receptor type 4; CXC-R4; CXCR-4; Fusin; Leukocyte-derived seven transmembrane domain receptor (LESTR); Pre-B-cell-derived chemokine receptor (PB-CKR); Stromal cell-derived factor 1 receptor (SDF-1 receptor); Cxcr4; Cmkar4; Lestr; Sdf1r

  • 细胞定位

    Cell membrane, Lysosome, Cell junction, Endosome

  • Accession

    P70658

  • 克隆号

    S-R670

  • 抗体类型

    Rat mAb

  • 抗体同种型

    IgG2b,k

  • 应用

    FCM

  • 反应种属 ?

    Ms

  • 阳性样本

    C57BL/6 mouse thymocytes

  • 纯化方式

    Protein G

  • 浓度

    0.05mg/ml

  • 标记

    Alexa Fluor® 647

  • 性状

    Liquid

  • 缓冲体系

    PBS, 25% Glycerol, 1% BSA, 0.3% Proclin 300

  • 储存条件

    12 months from date of receipt / reconstitution, 2 to 8 °C as supplied.
稀释度
应用 稀释度 推荐种属
FCM 5μl per million cells in 100μl volume Ms
背景介绍

  • CD184, also known as CXCR4, is a CXC chemokine receptor encoded by the CXCR4 gene. It is a G protein-coupled receptor that specifically binds to stromal-derived factor-1 (SDF-1, also known as CXCL12), which is important for lymphocyte chemotaxis, hematopoietic stem cell homing, and quiescence. CXCR4 is also a co-receptor for HIV infection in CD4+ T cells, particularly for T-cell tropic HIV strains. Additionally, CXCR4 is involved in neuronal guidance during embryogenesis and adult life, and its dysregulation has been implicated in various diseases, including cancer and epilepsy.

  • 流式分析

    • Flow cytometric analysis of Mouse CD184 expression on C57BL/6 mouse thymocytes. C57BL/6 mouse thymocytes were stained with Brilliant Violet 421™ Rat Anti-Mouse CD4 Antibody and either Alexa Fluor® 647 Rat IgG2b, κ Isotype Control (Left panel) or SDT Alexa Fluor® 647 Rat Anti-Mouse CD184 Antibody (Right panel) at 5μl/test. Flow cytometry and data analysis were performed using BD FACSymphony™ A1 and FlowJo™ software.

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