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宿主来源
Armenian hamster抗原名称
Mouse CD196分子别名
C-C chemokine receptor type 6; C-C CKR-6; CC-CKR-6; CCR-6; KY411; Ccr6; Cmkbr6细胞定位
Cell membraneAccession
O54689克隆号
S-R621抗体类型
Recombinant mAb抗体同种型
IgG应用
FCM反应种属 ?
Ms阳性样本
C57BL/6 mouse splenocytes纯化方式
Protein G浓度
0.05mg/ml标记
Alexa Fluor® 647性状
Liquid缓冲体系
PBS, 25% Glycerol, 1% BSA, 0.3% Proclin 300
储存条件
12 months from date of receipt / reconstitution, 2 to 8 °C as supplied.
| 应用 | 稀释度 | 推荐种属 |
|---|---|---|
| FCM | 5μl per million cells in 100μl volume | Ms |
CD196, also known as CCR6, is a seven-transmembrane, G-protein-coupled receptor that belongs to the beta chemokine receptor family. It is predominantly expressed on B lymphocytes, certain subsets of effector and memory T cells, and immature dendritic cells. CCR6 is a receptor for the CC chemokine CCL20 and also binds with lower affinity to beta-defensin 2. This receptor plays a crucial role in mediating the trafficking of immune cells to epithelial sites near the skin and mucosal surfaces during inflammatory and immunological responses.
流式分析
Flow cytometric analysis of Mouse CD196 expression on C57BL/6 mouse splenocytes. C57BL/6 mouse splenocytes were stained with FITC Rat Anti-Mouse CD45R/B220 Antibody and either Alexa Fluor® 647 Armenian hamster IgG Isotype Control (Left panel) or SDT Alexa Fluor® 647 Armenian hamster Anti-Mouse CD196 Antibody (Right panel) at 5μl/test. Flow cytometry and data analysis were performed using BD FACSymphony™ A1 and FlowJo™ software.
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