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宿主来源
Rat抗原名称
Mouse CD185分子别名
C-X-C chemokine receptor type 5; CXC-R5; CXCR-5; Burkitt lymphoma receptor 1 homolog; Cxcr5; Blr1; Gpcr6细胞定位
Cell membraneAccession
Q04683克隆号
S-R600抗体类型
Rat mAb抗体同种型
IgG2b,k反应种属 ?
Ms阳性样本
C57BL/6 mouse splenocytes纯化方式
Protein G浓度
2 mg/ml标记
Unconjugated性状
Liquid缓冲体系
PBS pH7.4
储存条件
12 months from date of receipt / reconstitution, 2 to 8 °C as supplied.应用
FCM
稀释度
应用 稀释度 推荐种属 FCM 1:200 Ms
CD185, also known as CXCR5 (C-X-C motif chemokine receptor 5), is a seven-transmembrane G protein-coupled receptor primarily expressed on mature B cells, follicular helper T cells (Tfh), and certain memory T cell subsets. It is essential for lymphocyte trafficking, particularly in directing T cells to B cell follicles within germinal centers in response to its ligand, CXCL13. CD185 plays a critical role in B cell maturation and the formation of high-affinity antibodies by facilitating interactions between Tfh cells and B cells. Additionally, it is involved in the regulation of neural stem cells and neuronal regeneration.
流式分析
Flow cytometric analysis of C57BL/6 mouse splenocytes labelling Mouse CD185 antibody at 1/200 (1 μg) dilution/ (Right panel) compared with a Rat IgG2b, κ Isotype Control / (Left panel). Goat Anti-Rat IgG Alexa Fluor® 647 was used as the secondary antibody. Then cells were stained with CD19 - Brilliant Violet 421™ Antibody separately.
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