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宿主来源
Armenian hamster抗原名称
Mouse CD36分子别名
Platelet glycoprotein 4; Glycoprotein IIIb (GPIIIB); PAS IV; PAS-4; Platelet glycoprotein IV (GPIV)细胞定位
Cell membraneAccession
Q08857克隆号
HM36抗体类型
Recombinant mAb抗体同种型
IgG反应种属 ?
Ms阳性样本
mouse peritoneal exudates cells纯化方式
Protein G浓度
0.2 mg/ml标记
FITC性状
Liquid缓冲体系
PBS, 1% BSA, 0.3% Proclin 300储存条件
12 months from date of receipt / reconstitution, 2 to 8 °C as supplied.应用
FCM
稀释度
应用 稀释度 推荐种属 FCM 5μl per million cells in 100μl volume Ms
CD36 is a multifunctional transmembrane glycoprotein belonging to the class B scavenger receptor family. It is widely expressed in platelets, mononuclear phagocytes, adipocytes, hepatocytes, muscle cells, and various epithelial cells. CD36 plays a crucial role in lipid metabolism by binding and transporting long-chain fatty acids (LCFAs) and oxidized low-density lipoprotein (ox-LDL), facilitating lipid uptake and metabolism in cells. In atherosclerosis, CD36 contributes to plaque formation by promoting the transformation of macrophages into foam cells through the uptake of ox-LDL. Additionally, CD36 is involved in immune regulation, influencing inflammatory responses, platelet activation, and tumor progression. In the tumor microenvironment, high expression of CD36 is associated with tumor cell invasion, metastasis, and immune suppression. Targeting CD36 has shown potential for inhibiting tumor growth and enhancing anti-tumor immunity.
流式分析
Flow cytometric analysis of Mouse CD36 expression on mouse peritoneal exudates cells. Mouse peritoneal exudates cells were stained with APC Rat Anti-Mouse F4/80 Antibody and either FITC Armenian Hamster IgG Isotype Control (Left panel) or SDT FITC Armenian Hamster Anti-Mouse CD36 Antibody (Right panel) at 5μl/test. Flow cytometry and data analysis were performed using BD FACSymphony™ A1 and FlowJo™ software.
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