Biotin Mouse Anti-Human CD56 Antibody (S-577-58)
CD56,C-type lectin domain family 13 member E,Endocytic receptor 180,Macrophage mannose receptor 2,NCAM1,NCAM,N-CAM-1,NCAM-1,Urokinase-type plasminogen activator receptor-associated protein,UPAR-associated protein,Urokinase receptor-associated protein,Neural cell adhesion molecule 1
货号： S0B5005
- 价格： ￥980
- 规格：
- 数量：
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别名
CD56,C-type lectin domain family 13 member E,Endocytic receptor 180,Macrophage mannose receptor 2,NCAM1,NCAM,N-CAM-1,NCAM-1,Urokinase-type plasminogen activator receptor-associated protein,UPAR-associated protein,Urokinase receptor-associated protein,Neural cell adhesion molecule 1宿主来源
Mouse抗原名称
CD56免疫原
Recombinant Protein细胞定位
Cell membraneAccession
P13591克隆号
S-577-58抗体类型
Mouse mAb抗体同种型
IgG1,λ应用
FCM反应种属 ?
Hu阳性样本
Human PBMC纯化方式
Protein G浓度
0.2 mg/ml标记
Biotin性状
Liquid缓冲体系
PBS pH7.4, 0.03% Proclin 300
储存条件
12 months from date of receipt / reconstitution, 2 to 8 °C as supplied.
| 应用 | 稀释度 | 推荐种属 |
|---|---|---|
| FCM | 5μl per million cells in 100μl volume | Hu |
Neural cell adhesion molecule (NCAM), also called CD56, is a homophilic binding glycoprotein expressed on the surface of neurons, glia and skeletal muscle. CD56 is thought to signal to induce neurite outgrowth via the fibroblast growth factor receptor (FGFR) and act upon the p59Fyn signaling pathway. In nerves, CD56 regulates homophilic (like-like) interactions between neurons and between neurons and muscle; it associates with fibroblast growth factor receptor (FGFR) and stimulates tyrosine kinase activity of receptor to induce neurite outgrowth. When neural crest cells stop making CD56 and N-cadherin, and start displaying integrin receptors, cells separate and migrate. During hematopoiesis, CD56 is the prototypic marker of NK cells, also present on subset of CD4+ T cells and CD8+ T cells. In cell adhesion, CD56 contributes to cell-cell adhesion or cell-matrix adhesion during embryonic development.
流式分析
Flow cytometric analysis of Human CD56 expression on human PBMC (human peripheral blood mononuclear cell). Human PBMC were stained with Brilliant Violet 421™ Mouse Anti-Human CD3 and either Biotin Isotype Control (Left panel) or SDT Biotin Mouse Anti-Human CD56 Antibody (Right panel) at 5μl/test followed by Sav-iFluor 488. Flow cytometry and data analysis were performed using BD FACSymphony™ A1 and FlowJo™ software.
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