Alexa Fluor® 647 Mouse Anti-Human CD59 Antibody (S-R567)
CD59 glycoprotein,1F5 antigen,20 kDa homologous restriction factor (HRF-20,HRF20),MAC-inhibitory protein (MAC-IP),MEM43 antigen,Membrane attack complex inhibition factor (MACIF),Membrane inhibitor of reactive lysis (MIRL),Protectin
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宿主来源
Mouse抗原名称
Human CD59分子别名
CD59 glycoprotein; 1F5 antigen; 20 kDa homologous restriction factor (HRF-20; HRF20); MAC-inhibitory protein (MAC-IP); MEM43 antigen; Membrane attack complex inhibition factor (MACIF); Membrane inhibitor of reactive lysis (MIRL); Protectin细胞定位
Cell membraneAccession
P13987克隆号
S-R567抗体类型
Mouse mAb抗体同种型
IgG2a反应种属 ?
Hu阳性样本
Human peripheral blood纯化方式
Protein A浓度
0.05mg/ml标记
Alexa Fluor® 647性状
Liquid缓冲体系
PBS, 1% BSA, 0.3% Proclin 300储存条件
12 months from date of receipt / reconstitution, 2 to 8 °C as supplied.应用
FCM
稀释度
应用 稀释度 推荐种属 FCM 5μl per million cells in 100μl volume Hu
CD59, also known as protectin, is a glycosylphosphatidylinositol (GPI)-anchored protein expressed on the surface of various cells. It plays a vital role in regulating the immune system and protecting cells from the complement system. Specifically, CD59 is the only membrane-bound inhibitor of the complement membrane attack complex (MAC), an immune pore that can damage human cells. Without CD59, MAC pores formed on red blood cells result in rupture, causing chronic hemolysis and immune-related neuropathies.
流式分析
Flow cytometric analysis of Human CD59 expression on human peripheral blood. Human peripheral blood was stained with Alexa Fluor® 647 Mouse IgG2a Isotype Control (Black line histogram) and SDT Alexa Fluor® 647 Mouse Anti-Human CD59 Antibody (Red line histogram) at 5μl/test, cells without incubation with primary antibody and secondary antibody (Blue line histogram) was used as unlabelled control. Flow cytometry and data analysis were performed using BD FACSymphony™ A1 and FlowJo™ software.
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