Mouse C5a Recombinant mAb (SDT-2557-122)

C5a is a critical biomarker and mediator of inflammation in preclinical research. C5a is a potent pro-inflammatory peptide released during complement activation. Measuring its levels in mouse models is essential for studying the pathogenesis of numerous inflammatory diseases, including sepsis, rheumatoid arthritis, and acute lung injury. Quantifying mouse C5a allows researchers to assess the degree of complement activation, evaluate the efficacy of novel therapeutics (such as C5a receptor antagonists or anti-inflammatory compounds), and understand the link between innate and adaptive immunity. Detection is typically performed using a sandwich-ELISA, which provides a quantitative, sensitive, and specific method for measuring C5a concentrations in various biological samples like serum, plasma, and tissue homogenates. Ultimately, detecting mouse C5a is fundamental for translating findings from mouse models of inflammation to potential human therapies.