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产品规格
宿主来源
Rabbit抗原名称
PSD-95分子别名
Disks large homolog 4; Postsynaptic density protein 95 (PSD-95); Synapse-associated protein 90 (SAP-90; SAP90); Dlgh4; Psd95; Dlg4免疫原
Recombinant ProteinAccession
Q62108克隆号
SDT-1518-140抗体类型
Recombinant mAb抗体同种型
IgG反应种属 ?
Hu交叉反应
No cross-reactivity against SNAP25, NFL, GFAP, Tau, UCHL1
纯化方式
Protein A浓度
2 mg/ml标记
Unconjugated性状
Liquid缓冲体系
PBS pH7.4, 0.03% Proclin 300
储存条件
12 months from date of receipt, 2 to 8 °C as supplied
应用
Sandwich ELISA
背景介绍
PSD-95 (postsynaptic density protein 95) is a 95-kDa scaffolding protein enriched in the postsynaptic density of excitatory synapses, where its three N-terminal PDZ domains, an SH3 domain, and a C-terminal guanylate kinase-like domain assemble transmembrane receptors, ion channels, adhesion molecules, and downstream signaling enzymes into a dynamic macromolecular signaling lattice that couples synaptic activity to postsynaptic potentiation or depression and whose dysregulation contributes to autism, schizophrenia, and stroke.
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