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产品规格
宿主来源
Rabbit抗原名称
TSLP分子别名
Thymic stromal lymphopoietin; TSLP免疫原
Recombinant ProteinAccession
Q969D9克隆号
SDT-2587-51-2抗体类型
Recombinant mAb抗体同种型
IgG反应种属 ?
Hu交叉反应
No cross reactivity against IL-6, IFN-γ, GM-CSF
纯化方式
Protein A浓度
2 mg/ml标记
Unconjugated性状
Liquid缓冲体系
PBS pH7.4, 0.03% Proclin 300
储存条件
12 months from date of receipt, 2 to 8 °C as supplied
应用
Sandwich ELISA
背景介绍
TSLP (thymic stromal lymphopoietin) is a four-helix-bundle cytokine of the IL-2 family that is chiefly produced by epithelial cells at barrier surfaces; it acts on dendritic cells, mast cells, and type 2 innate lymphoid cells via a receptor complex of TSLPR plus IL-7Rα to trigger STAT5-driven transcriptional programs, thereby polarizing naïve CD4⁺ T cells toward a pro-allergic Th2 phenotype, orchestrating eosinophilic inflammation, and serving as a master switch for atopic dermatitis, asthma, and other allergic diseases.
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