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TSLP Recombinant Rabbit mAb (SDT-2587-51)

Thymic stromal lymphopoietin,TSLP

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货号 S0B3612
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产品规格
  • 宿主来源

    Rabbit
  • 抗原名称

    TSLP
  • 分子别名

    Thymic stromal lymphopoietin; TSLP
  • 免疫原

    Recombinant Protein
  • Accession

    Q969D9
  • 克隆号

    SDT-2587-51
  • 抗体类型

    Recombinant mAb
  • 抗体同种型

    IgG
  • 反应种属 ?

    Hu
  • 交叉反应

    No cross-reactivity against IL-6, IFN-γ, GM-CSF

  • 纯化方式

    Protein A
  • 浓度

    2 mg/ml
  • 标记

    Unconjugated
  • 性状

    Liquid
  • 缓冲体系

    PBS pH7.4, 0.03% Proclin 300

  • 储存条件

    12 months from date of receipt, 2 to 8 °C as supplied

  • 应用

    Sandwich ELISA

背景介绍
  • TSLP (thymic stromal lymphopoietin) is a four-helix-bundle cytokine of the IL-2 family that is chiefly produced by epithelial cells at barrier surfaces; it acts on dendritic cells, mast cells, and type 2 innate lymphoid cells via a receptor complex of TSLPR plus IL-7Rα to trigger STAT5-driven transcriptional programs, thereby polarizing naïve CD4⁺ T cells toward a pro-allergic Th2 phenotype, orchestrating eosinophilic inflammation, and serving as a master switch for atopic dermatitis, asthma, and other allergic diseases.

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