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Rabbit抗原名称
ICAM-1/CD54分子别名
Intercellular adhesion molecule 1; ICAM-1; Major group rhinovirus receptor; CD54; ICAM1免疫原
Recombinant ProteinAccession
P05362克隆号
SDT-2461-2抗体类型
Recombinant mAb抗体同种型
IgG反应种属 ?
Hu交叉反应
No cross-reactivity against L-selectin, E-selectin, VCAM-1.
纯化方式
Protein A浓度
2 mg/ml标记
Unconjugated性状
Liquid缓冲体系
PBS pH7.4, 0.03% Proclin 300
储存条件
12 months from date of receipt, 2 to 8 °C as supplied
应用
Sandwich ELISA
Soluble Intercellular Adhesion Molecule-1 (sICAM-1) is found in the bloodstream and originates from the proteolytic cleavage of membrane-bound ICAM-1 (found on endothelial and immune cells). Elevated serum levels are primarily a marker of endothelial activation and systemic inflammation. Meanwhile, while serum ICAM-1 is not a disease-specific diagnostic test, it serves as a valuable and sensitive marker of systemic endothelial activation and inflammation. Its measurement provides insight into the activity and severity of various conditions, particularly in cardiovascular, autoimmune, and oncologic diseases, and can help in risk stratification and monitoring.
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