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ICAM-1/CD54 Recombinant Rabbit mAb (SDT-2461-88)

Intercellular adhesion molecule 1,ICAM-1,Major group rhinovirus receptor,CD54,ICAM1

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货号 S0B3577
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产品介绍

产品介绍 评论(0)

产品规格

  • 宿主来源

    Rabbit

  • 抗原名称

    ICAM-1/CD54

  • 分子别名

    Intercellular adhesion molecule 1; ICAM-1; Major group rhinovirus receptor; CD54; ICAM1

  • 免疫原

    Recombinant Protein

  • Accession

    P05362

  • 克隆号

    SDT-2461-88

  • 抗体类型

    Recombinant mAb

  • 抗体同种型

    IgG

  • 反应种属 ?

    Hu

  • 交叉反应

    No cross-reactivity against L-selectin, E-selectin, VCAM-1.

  • 纯化方式

    Protein A

  • 浓度

    2 mg/ml

  • 标记

    Unconjugated

  • 性状

    Liquid

  • 缓冲体系

    PBS pH7.4, 0.03% Proclin 300

  • 储存条件

    12 months from date of receipt, 2 to 8 °C as supplied

  • 应用

    Sandwich ELISA

背景介绍

  • Soluble Intercellular Adhesion Molecule-1 (sICAM-1) is found in the bloodstream and originates from the proteolytic cleavage of membrane-bound ICAM-1 (found on endothelial and immune cells). Elevated serum levels are primarily a marker of endothelial activation and systemic inflammation. Meanwhile, while serum ICAM-1 is not a disease-specific diagnostic test, it serves as a valuable and sensitive marker of systemic endothelial activation and inflammation. Its measurement provides insight into the activity and severity of various conditions, particularly in cardiovascular, autoimmune, and oncologic diseases, and can help in risk stratification and monitoring.

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