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Mouse IL-13 Recombinant mAb (SDT-2177-10)

Interleukin-13,T-cell activation protein P600

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货号 S0B3575
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产品介绍

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产品规格

  • 宿主来源

    Rabbit

  • 抗原名称

    Mouse IL-13

  • 分子别名

    Interleukin-13; T-cell activation protein P600

  • 免疫原

    Recombinant Protein

  • 克隆号

    SDT-2177-10

  • 抗体类型

    Recombinant mAb

  • 抗体同种型

    IgG

  • 反应种属 ?

    Ms

  • 交叉反应

    No cross-reactivity against mouse GM-CSF, IL-1β, IL-1α

  • 纯化方式

    Protein A

  • 浓度

    2 mg/ml

  • 标记

    Unconjugated

  • 性状

    Liquid

  • 缓冲体系

    PBS pH7.4, 0.03% Proclin 300

  • 储存条件

    12 months from date of receipt, 2 to 8 °C as supplied

  • 应用

    Sandwich ELISA

背景介绍

  • IL-13 (Interleukin-13) is a key cytokine primarily produced by activated Th2 cells, mast cells, and basophils. It is a central mediator in type 2 immune responses, playing a critical role in the pathogenesis of allergic inflammation. Its main functions include inducing IgE class switching in B cells, promoting mucus hypersecretion in airway epithelial cells, and contributing to tissue fibrosis by stimulating fibroblast proliferation and collagen production. Furthermore, IL-13 is instrumental in the defense against helminthic parasites by facilitating their expulsion from the gastrointestinal tract.

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