热搜词：
注册
登录
CN
  • CN
  • EN

产品中心 抗体 配对抗体

所有图片（1/1）

mouse IL-12 p40 Recombinant mAb (SDT-1778-97)

Interleukin-12 subunit beta,IL-12B,Cytotoxic lymphocyte maturation factor 40 kDa subunit (CLMF p40),IL-12 subunit p40

价格 询价 请咨询客服
货号 S0B3532
规格
数量
收藏 分享
产品介绍

产品介绍 评论(0)

产品规格

  • 宿主来源

    Rabbit

  • 抗原名称

    IL-12 p40

  • 分子别名

    Interleukin-12 subunit beta; IL-12B; Cytotoxic lymphocyte maturation factor 40 kDa subunit (CLMF p40); IL-12 subunit p40

  • 免疫原

    Recombinant Protein

  • 细胞定位

    Secreted

  • Accession

    P43432

  • 克隆号

    SDT-1778-97

  • 反应种属 ?

    Ms

  • 交叉反应

    No cross-reactivity against human il-12, mouse il-2, mouse il-4, mouse il-6, mouse il-7, mouse il-10 and mouse TNF alpha

  • 浓度

    2 mg/ml

  • 纯度

    >95% by HPLC

  • 性状

    Liquid

  • 缓冲体系

    PBS pH7.4, 0.03% Proclin 300

  • 储存条件

    12 months from date of receipt, 2 to 8 °C as supplied

  • 应用

    Sandwich ELISA

背景介绍

  • Interleukin-12 p70 (IL-12 p70) is a disulfide-linked heterodimeric cytokine composed of a 35-kDa light chain (p35) and a 40-kDa heavy chain (p40), functioning as the biologically active form of IL-12 secreted primarily by antigen-presenting cells such as dendritic cells, macrophages, and B cells upon recognition of pathogens; it drives the differentiation of naïve CD4+ T cells toward the Th1 phenotype, synergizes with IL-18 to induce large amounts of IFN-γ from T and NK cells, bridges innate and adaptive immunity, and is implicated in protective immunity against intracellular bacteria, viruses, and tumors, yet its dysregulation contributes to autoimmune and inflammatory disorders.

  • 配对推荐

评论(0)