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IL-3 Recombinant Rabbit mAb (SDT-836-159-2)

Interleukin-3,IL-3,Hematopoietic growth factor,Mast cell growth factor (MCGF),Multipotential colony-stimulating factor,P-cell-stimulating factor,IL3

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货号 S0B3485
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产品介绍

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产品规格

  • 宿主来源

    Rabbit

  • 抗原名称

    IL-3

  • 分子别名

    Interleukin-3; IL-3; Hematopoietic growth factor; Mast cell growth factor (MCGF); Multipotential colony-stimulating factor; P-cell-stimulating factor; IL3

  • 免疫原

    Recombinant Protein

  • Accession

    P08700

  • 克隆号

    SDT-836-159-2

  • 抗体类型

    Recombinant mAb

  • 抗体同种型

    IgG

  • 反应种属 ?

    Hu

  • 交叉反应

    No cross-reactivity against human IL-2, IL-4, IL-7, IL-9, IL-10, IL-15 and GM-CSF

  • 纯化方式

    Protein A

  • 浓度

    2 mg/ml

  • 纯度

    >95% by HPLC

  • 标记

    Unconjugated

  • 性状

    Liquid

  • 缓冲体系

    PBS pH7.4, 0.03% Proclin 300

  • 储存条件

    12 months from date of receipt, 2 to 8 °C as supplied

  • 应用

    Sandwich ELISA

背景介绍

  • Interleukin 3 (IL - 3) is a multifunctional cytokine that plays a crucial role in the regulation of hematopoiesis. It is primarily produced by activated T cells and mast cells. IL - 3 can stimulate the proliferation and differentiation of various hematopoietic cells, including myeloid, erythroid, and megakaryocytic progenitor cells. It acts by binding to its specific receptor, which is mainly expressed on the surface of hematopoietic cells. This binding activates a series of intracellular signaling pathways, promoting cell growth and survival. IL - 3 also has immunomodulatory functions, such as enhancing the activity of natural killer cells and macrophages. In addition, it is involved in the inflammatory response and tissue repair processes. Abnormal expression or function of IL - 3 has been associated with certain hematological disorders and immune - related diseases.

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