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Human IgM Recombinant mAb (SDT-1465-25)

Immunoglobulin heavy constant mu,Ig mu chain C region,Ig mu chain C region BOT,Ig mu chain C region GAL,Ig mu chain C region OU,IGHM

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货号 S0B3479
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产品介绍

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产品规格

  • 宿主来源

    Rabbit

  • 抗原名称

    Human IgM

  • 分子别名

    Immunoglobulin heavy constant mu; Ig mu chain C region; Ig mu chain C region BOT; Ig mu chain C region GAL; Ig mu chain C region OU; IGHM

  • 细胞定位

    Cell membrane, Secreted

  • Accession

    P01871

  • 克隆号

    SDT-1465-25

  • 反应种属 ?

    Hu

  • 交叉反应

    No cross-reactivity against human IgG, human IgE, mouse serum, rat serum, weak cross-reactivity against human IgA

  • 浓度

    2 mg/ml

  • 纯度

    >95% by HPLC

  • 性状

    Liquid

  • 缓冲体系

    PBS pH7.4, 0.03% Proclin 300

  • 储存条件

    12 months from date of receipt, 2 to 8 °C as supplied

  • 应用

    Sandwich ELISA

    CLIA

背景介绍

  • Human IgM is the first type of antibody produced by the body in response to an initial exposure to an antigen. It is a large, pentameric molecule, composed of five identical Y-shaped units linked together. Each IgM molecule has ten antigen-binding sites, which allows it to be highly effective at agglutinating pathogens. IgM is primarily found in the bloodstream and plays a crucial role in the early stages of the immune response. It can activate the complement system, enhancing the ability to eliminate pathogens. Additionally, the presence of IgM antibodies in diagnostic tests often indicates a recent infection, as it appears earlier than other types of antibodies like IgG.

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