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Rabbit抗原名称
Mouse CCL2/JE/MCP-1分子别名
C-C motif chemokine 2; Monocyte chemoattractant protein 1; Monocyte chemotactic protein 1 (MCP-1); Platelet-derived growth factor-inducible protein JE; Small-inducible cytokine A2; Je; Mcp1; Scya2; Ccl2免疫原
Recombinant ProteinAccession
P10148克隆号
SDT-1794-21抗体类型
Recombinant mAb抗体同种型
IgG反应种属 ?
Ms交叉反应
No cross-reactivity against mouse CXCL14 and mouse MARCO
纯化方式
Protein A浓度
2 mg/ml标记
Unconjugated性状
Liquid缓冲体系
PBS pH7.4, 0.03% Proclin 300
储存条件
12 months from date of receipt, 2 to 8 °C as supplied
应用
Sandwich ELISA
Mouse CCL2, also known as JE or MCP-1 (Monocyte Chemoattractant Protein-1), is a cytokine that belongs to the CC chemokine family. It is primarily produced by monocytes, macrophages, and various other cell types in response to inflammatory stimuli. CCL2 plays a crucial role in the recruitment and activation of monocytes, memory T cells, and dendritic cells to sites of inflammation, thereby contributing to the immune response. This protein is involved in various physiological and pathological processes, including the regulation of immune cell migration during inflammation, the development of atherosclerosis, and the progression of certain cancers. Its expression and activity are tightly regulated, and dysregulation of CCL2 has been implicated in numerous diseases, making it a potential target for therapeutic interventions.
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