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Mouse IL-2 Recombinant mAb (SDT-2117-6)

Interleukin-2,T-cell growth factor (TCGF),Il-2,Il2

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货号 S0B3439
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产品规格
  • 宿主来源

    Rabbit
  • 抗原名称

    IL-2
  • 分子别名

    Interleukin-2; T-cell growth factor (TCGF); Il-2; Il2
  • 免疫原

    Recombinant Protein
  • Accession

    P04351
  • 克隆号

    SDT-2117-6
  • 抗体类型

    Recombinant mAb
  • 抗体同种型

    IgG
  • 反应种属 ?

    Ms
  • 交叉反应

    No cross-reactivity against mouse IL-4, IL-6, GM-CSF, rat IL-2.

  • 纯化方式

    Protein A
  • 浓度

    2 mg/ml
  • 标记

    Unconjugated
  • 性状

    Liquid
  • 缓冲体系

    PBS pH7.4, 0.03% Proclin 300

  • 储存条件

    12 months from date of receipt, 2 to 8 °C as supplied

  • 应用

    Sandwich ELISA

背景介绍
  • Interleukin-2 (IL-2) is a cytokine that plays a crucial role in the immune system. It is primarily produced by activated T cells and has multiple functions. Mature mouse IL-2 shares 56% and 73% aa identity with human and rat IL-2, respectively. IL-2 promotes the proliferation and differentiation of T cells, enhancing their ability to fight infections and tumors. It also stimulates the growth and activity of natural killer (NK) cells, which are important for immune defense. Additionally, IL-2 can regulate the activity of regulatory T cells (Tregs), helping to maintain immune tolerance and prevent autoimmune diseases. In clinical settings, IL-2 has been used to treat certain cancers by boosting the immune response, although its use is limited due to potential side effects. Its discovery and research have significantly advanced our understanding of the immune system and provided new strategies for immunotherapy.

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